Sulfonation of papain-treated chitosan and its mechanism for anticoagulant activity

The novel low-molecular-weight chitosan polysulfate (MW 5120-26,200 Da) was prepared using the depolymerization of chitosan with papain (EC. 3.4.22.2). The sulfonation of depolymerized products was performed using chlorosulfonic acid in N,N-dimethylformamide under semi-heterogeneous conditions. The...

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Bibliographic Details
Main Authors: Suwan J., Zhang Z., Li B., Vongchan P., Meepowpan P., Zhang F., Mousa S.A., Mousa S., Premanode B., Kongtawelert P., Linhardt R.J.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-66649109421&partnerID=40&md5=672381a5fcbe04a59556100de1650ff7
http://www.ncbi.nlm.nih.gov/pubmed/19476923
http://cmuir.cmu.ac.th/handle/6653943832/5853
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Institution: Chiang Mai University
Language: English
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