Maternal neutralizing antibodies against a CRF01_AE primary isolate are associated with a low rate of intrapartum HIV-1 transmission

• Main Authors: Tanawan Samleerat, Suzie Thenin, Gonzague Jourdain, Nicole Ngo-Giang-Huong, Alain Moreau, Pranee Leechanachai, Jirapan Ithisuknanth, Karin Pagdi, Pornpun Wannarit, Suraphan Sangsawang, Marc Lallemant, Francis Barin, Martine Braibant
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=64849106636&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59636
• Institution: Chiang Mai University

Mother-to-child transmission (MTCT) of HIV-1 provides a model for studying the role of passively acquired antibodies in preventing HIV infection. We determined the titers of neutralizing antibodies (NAbs) against six primary isolates of clades B and CRF01_AE in sera from 45 transmitting and 45 nontr...