SOX9 transduction increases chondroitin sulfate synthesis in cultured human articular chondrocytes without altering glycosyltransferase and sulfotransferase transcription

The transcription factor SOX9 (Sry-type high-mobility-group box 9) is expressed in all chondrocytes and is essential for the expression of aggrecan, which during biosynthesis is substituted with more than 10 times; its weight of CS (chondroitin sulfate) and is secreted by chondrocytes to form the ch...

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Main Authors: Simon R. Tew, Peraphan Pothacharoen, Theoni Katopodi, Timothy E. Hardingham
格式: 雜誌
出版: 2018
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在線閱讀:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=50949114221&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/60150
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機構: Chiang Mai University