SOX9 transduction increases chondroitin sulfate synthesis in cultured human articular chondrocytes without altering glycosyltransferase and sulfotransferase transcription
The transcription factor SOX9 (Sry-type high-mobility-group box 9) is expressed in all chondrocytes and is essential for the expression of aggrecan, which during biosynthesis is substituted with more than 10 times; its weight of CS (chondroitin sulfate) and is secreted by chondrocytes to form the ch...
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Main Authors: | Simon R. Tew, Peraphan Pothacharoen, Theoni Katopodi, Timothy E. Hardingham |
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Format: | Journal |
Published: |
2018
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Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=50949114221&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/60150 |
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Institution: | Chiang Mai University |
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