Superoxide-mediated proteasomal degradation of Bcl-2 determines cell susceptibility to Cr(VI)-induced apoptosis

Hexavalent chromium [Cr(VI)] compounds are redox cycling environmental carcinogens that induce apoptosis as the primary mode of cell death. Defects in apoptosis regulatory mechanisms contribute to carcinogenesis induced by Cr(VI). Activation of apoptosis signaling pathways is tightly linked with the...

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Bibliographic Details
Main Authors: Neelam Azad, Anand Krishnan V. Iyer, Aranya Manosroi, Liying Wang, Yon Rojanasakul
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=49649083897&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/60153
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Institution: Chiang Mai University

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