Isoflavones and rotenoids from the leaves of Millettia brandisiana

A new isoflavone, 4′-γ,γ-dimethylallyloxy-5,7,2′, 5′-tetramethoxyisoflavone, brandisianin A (1), was isolated from the leaves of Millettia brandisiana, along with one synthetically known isoflavone, 7,4′-di-O-prenylgenistein (2) and twelve known compounds. The structures were elucidated on the basis...

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Bibliographic Details
Main Authors: Orasa Pancharoen, Anan Athipornchai, Ampai Panthong, Walter Charles Taylor
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=45749126020&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/60251
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Institution: Chiang Mai University
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Summary:A new isoflavone, 4′-γ,γ-dimethylallyloxy-5,7,2′, 5′-tetramethoxyisoflavone, brandisianin A (1), was isolated from the leaves of Millettia brandisiana, along with one synthetically known isoflavone, 7,4′-di-O-prenylgenistein (2) and twelve known compounds. The structures were elucidated on the basis of extensive spectroscopic analysis. Two isolated compounds were tested for anti-inflammatory activity; 12a-hydroxy-α- toxicarol (11) showed significant anti-inflammatory activity. © 2008 Pharmaceutical Society of Japan.