Comparison of the TaqMan and LightCycler systems in evaluation of CYP2B6 516G>T polymorphism

• Main Authors: Soranun Chantarangsu, Tim Cressey, Surakameth Mahasirimongkol, Yardpiroon Tawon, Nicole Ngo-Giang-Huong, Gonzague Jourdain, Marc Lallemant, Wasun Chantratita
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34547928361&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60884
• Institution: Chiang Mai University

Understanding genetically encoded inherited differences in drug metabolism and drug targets offers the promise of minimizing adverse drug reactions and improving therapies. We have compared two real-time PCR-based methods, the TaqMan®and LightCycler™ for the pharmacogenetic evaluation of CYP2B6 516G...