Insight into Molecular Determinants of T3 vs T4 Recognition from Mutations in Thyroid Hormone Receptor α and β

Insight into Molecular Determinants of T3 vs T4 Recognition from Mutations in Thyroid Hormone Receptor α and β

© 2019 Endocrine Society. Context The two major forms of circulating thyroid hormones (THs) are T3 and T4. T3 is regarded as the biologically active hormone because it binds to TH receptors (TRs) with greater affinity than T4. However, it is currently unclear what structural mechanisms underlie this...

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Bibliographic Details
Main Authors: Karn Wejaphikul, Stefan Groeneweg, Yvonne Hilhorst-Hofstee, V. Krishna Chatterjee, Robin P. Peeters, Marcel E. Meima, W. Edward Visser
Format: Journal
Published: 2019
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066479373&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/65365
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Institution: Chiang Mai University

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http://cmuir.cmu.ac.th/jspui/handle/6653943832/65365

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