EMMPRIN reduction via scFv-M6-1B9 intrabody affects α3β1-integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2

EMMPRIN reduction via scFv-M6-1B9 intrabody affects α3β1-integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2

Extracellular matrix metalloproteinase inducer (EMMPRIN) exhibits overexpression in various cancers and promotes cancer progression and metastasis via the interaction with its associated molecules. The scFv-M6-1B9 intrabody has a potential ability to reduce EMMPRIN cell surface expression. However,...

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Main Authors: Sangboonruang S., Thammasit P., Intasai N., Kasinrerk W., Tayapiwatana C., Tragoolpua K.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84902024588&partnerID=40&md5=5393be25baf2d0a11e11aafe253e0f03
http://cmuir.cmu.ac.th/handle/6653943832/701
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Institution: Chiang Mai University
Language: English

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http://www.scopus.com/inward/record.url?eid=2-s2.0-84902024588&partnerID=40&md5=5393be25baf2d0a11e11aafe253e0f03
http://cmuir.cmu.ac.th/handle/6653943832/701

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