Inhibitory mechanism of pure curcumin on Wilms' tumor 1 (WT1) gene expression through the PKCα signaling pathway in leukemic K562 cells
The aim of this study was to investigate the inhibitory mechanism of pure curcumin on WT1 expression in leukemic K562 cells. Pure curcumin suppressed WT1 expression, independent of effects on protein degradation or WT1 mRNA stability. Chromatin immunoprecipitation and reporter gene assays indicate t...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-79960383409&partnerID=40&md5=6526c62524f779d17f4e27ab8c1cd4ae http://www.ncbi.nlm.nih.gov/pubmed/21658388 http://cmuir.cmu.ac.th/handle/6653943832/754 |
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| Institution: | Chiang Mai University |
| Language: | English |