Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse

Defective melanocortin signaling causes hyperphagic obesity in humans and the melanocortin-4 receptor knockout mouse (MC4R -/- ). The human disease most commonly presents, however, as haploinsufficiency of the MC4R. This study validates the MC4R +/- mouse as a model of the human disease in that, li...

Full description

Saved in:
Bibliographic Details
Main Authors: Dollada Srisai, Matthew P. Gillum, Brandon L. Panaro, Xian Man Zhang, Naiphinich Kotchabhakdi, Gerald I. Shulman, Kate L.J. Ellacott, Roger D. Cone
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/11582
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University