Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse
Defective melanocortin signaling causes hyperphagic obesity in humans and the melanocortin-4 receptor knockout mouse (MC4R -/- ). The human disease most commonly presents, however, as haploinsufficiency of the MC4R. This study validates the MC4R +/- mouse as a model of the human disease in that, li...
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Main Authors: | , , , , , , , |
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Other Authors: | |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/11582 |
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Institution: | Mahidol University |
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