Bordetella pertussis CyaA-RTX subdomain requires calcium ions for structural stability against proteolytic degradation

Previously, the 126-kDa Bordetella pertussis CyaA pore-forming (CyaA-PF) domain expressed in Escherichia coli was shown to retain its hemolytic activity. Here, a 100-kDa RTX (Repeat-in-ToXin) subcloned fragment (CyaA-RTX) containing a number of putative calcium-binding repeats was further investigat...

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Bibliographic Details
Main Authors: Pichaya Pojanapotha, Niramon Thamwiriyasati, Busaba Powthongchin, Gerd Katzenmeier, Chanan Angsuthanasombat
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/11593
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Institution: Mahidol University