The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs
When 14.0 mg/100 ml capsaicin was placed onto the serosal solution for 30 and 60 min, intestinal glucose transport was inhibited by 30.24 and 56.62% in the rat, and 25.87 and 40.83% in the hamster, respectively. A significantly smaller amount of capsaicin was absorbed into the gut wall, and none app...
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| Main Authors: | , |
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| Format: | Article |
| Published: |
2018
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/13286 |
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| Institution: | Mahidol University |
| Summary: | When 14.0 mg/100 ml capsaicin was placed onto the serosal solution for 30 and 60 min, intestinal glucose transport was inhibited by 30.24 and 56.62% in the rat, and 25.87 and 40.83% in the hamster, respectively. A significantly smaller amount of capsaicin was absorbed into the gut wall, and none appeared in the mucosal solution. It is suggested that capsaicin may inhibit the ATPasedependent sodium pump of the basolateral membrane, with consequent inhibition of intestinal glucose absorption. © 1979. |
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