The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs

When 14.0 mg/100 ml capsaicin was placed onto the serosal solution for 30 and 60 min, intestinal glucose transport was inhibited by 30.24 and 56.62% in the rat, and 25.87 and 40.83% in the hamster, respectively. A significantly smaller amount of capsaicin was absorbed into the gut wall, and none app...

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Main Authors: Yongyot Monsereenusorn, Thirayudth Glinsukon
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/13286
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spelling th-mahidol.132862018-06-01T13:32:10Z The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs Yongyot Monsereenusorn Thirayudth Glinsukon Mahidol University Pharmacology, Toxicology and Pharmaceutics When 14.0 mg/100 ml capsaicin was placed onto the serosal solution for 30 and 60 min, intestinal glucose transport was inhibited by 30.24 and 56.62% in the rat, and 25.87 and 40.83% in the hamster, respectively. A significantly smaller amount of capsaicin was absorbed into the gut wall, and none appeared in the mucosal solution. It is suggested that capsaicin may inhibit the ATPasedependent sodium pump of the basolateral membrane, with consequent inhibition of intestinal glucose absorption. © 1979. 2018-06-01T06:32:10Z 2018-06-01T06:32:10Z 1979-01-01 Article Toxicology Letters. Vol.4, No.5 (1979), 393-397 10.1016/0378-4274(79)90051-1 03784274 2-s2.0-0018690628 https://repository.li.mahidol.ac.th/handle/123456789/13286 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0018690628&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Pharmacology, Toxicology and Pharmaceutics
spellingShingle Pharmacology, Toxicology and Pharmaceutics
Yongyot Monsereenusorn
Thirayudth Glinsukon
The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs
description When 14.0 mg/100 ml capsaicin was placed onto the serosal solution for 30 and 60 min, intestinal glucose transport was inhibited by 30.24 and 56.62% in the rat, and 25.87 and 40.83% in the hamster, respectively. A significantly smaller amount of capsaicin was absorbed into the gut wall, and none appeared in the mucosal solution. It is suggested that capsaicin may inhibit the ATPasedependent sodium pump of the basolateral membrane, with consequent inhibition of intestinal glucose absorption. © 1979.
author2 Mahidol University
author_facet Mahidol University
Yongyot Monsereenusorn
Thirayudth Glinsukon
format Article
author Yongyot Monsereenusorn
Thirayudth Glinsukon
author_sort Yongyot Monsereenusorn
title The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs
title_short The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs
title_full The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs
title_fullStr The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs
title_full_unstemmed The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs
title_sort inhibitory effect of capsaicin on intestinal glucose absorption in vitro. i. effect of capsaicin on the serosal side of everted intestinal sacs
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/13286
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