Heterologous Expression of Active Thymidylate Synthase–Dihydrofolate Reductase from Plasmodium falciparum
The coding sequence of the bifunctional thymidylate synthase-dihydrofolate reductase (TS-DHFR) from a moderately pyrimethamine-resistant strain (HB3) of Plasmodium falciparum was assembled in a pUC expression vector. The coding sequence possesses unique Nco 1 and Xba1 sites which flank 243 bp of the...
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| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/15911 |
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| Institution: | Mahidol University |