A simple dual selection for functionally active mutants of Plasmodium falciparum dihydrofolate reductase with improved solubility
Sufficient solubility of the active protein in aqueous solution is a prerequisite for crystallization and other structural studies of proteins. In this study, we have developed a simple and effective in vivo screening system to select for functionally active proteins with increased solubility by usi...
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Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/16291 |
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Institution: | Mahidol University |