The choice of a genetic model in the meta-analysis of molecular association studies

Background: To evaluate gene-disease associations, genetic epidemiologists collect information on the disease risk in subjects with different genotypes (for a bi-allelic polymorphism: gg, Gg, GG). Meta-analyses of such studies usually reduce the problem to a single comparison, either by performing t...

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Bibliographic Details
Main Authors: Cosetta Minelli, John R. Thompson, Keith R. Abrams, Ammarin Thakkinstian, John Attia
Other Authors: University of Leicester
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/16712
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Institution: Mahidol University