Effect of grinding of β-cyclodextrin and glibenclamide on tablet properties. Part I. In vitro
Physical properties including dissolution characteristics of glibenclamide (GB) tablets were studied. Directly compressed and wet-granulated GB tablets gave only 35% and 40% drug dissolved, respectively. Physical mixing, kneading, and grinding of β-cyclodextrin (CD) with CB were investigated. It was...
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Main Authors: | , , , |
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Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/17582 |
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Institution: | Mahidol University |