Effect of grinding of β-cyclodextrin and glibenclamide on tablet properties. Part I. In vitro

Physical properties including dissolution characteristics of glibenclamide (GB) tablets were studied. Directly compressed and wet-granulated GB tablets gave only 35% and 40% drug dissolved, respectively. Physical mixing, kneading, and grinding of β-cyclodextrin (CD) with CB were investigated. It was...

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Bibliographic Details
Main Authors: Ampol Mitrevej, Nuttanan Sinchaipanid, Varaporn Junyaprasert, Ladda Warintornuwat
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/17582
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Institution: Mahidol University

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