Insertion of common mutations into the human β-globin locus using GET Recombination and an EcoRI endonuclease counterselection cassette

A large number of mutations have been described in the human β-globin locus causing thalassemia or various hemoglobinopathies. However, only a very limited number of these mutations have been studied in animal model systems in the context of the human β-globin locus. We report here the use of the GE...

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Bibliographic Details
Main Authors: Duangporn Jamsai, Mikhail Nefedov, Kumaran Narayanan, Michael Orford, Suthat Fucharoen, Robert Williamson, Panos A. Ioannou
Other Authors: Royal Children's Hospital, Melbourne
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/20760
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Institution: Mahidol University

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