Insertion of common mutations into the human β-globin locus using GET Recombination and an EcoRI endonuclease counterselection cassette
A large number of mutations have been described in the human β-globin locus causing thalassemia or various hemoglobinopathies. However, only a very limited number of these mutations have been studied in animal model systems in the context of the human β-globin locus. We report here the use of the GE...
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Main Authors: | Duangporn Jamsai, Mikhail Nefedov, Kumaran Narayanan, Michael Orford, Suthat Fucharoen, Robert Williamson, Panos A. Ioannou |
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Other Authors: | Royal Children's Hospital, Melbourne |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/20760 |
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Institution: | Mahidol University |
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