Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

Background The borders of Thailand harbour the world's most multidrug resistant Plasmodium falciparum parasites. In 1984 mefloquine was introduced as treatment for uncomplicated falciparum malaria, but substantial resistance developed within 6 years. A combination of artesunate with mefloquine...

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Bibliographic Details
Main Authors: Ric N. Price, Anne Catrin Uhlemann, Alan Brockman, Rose McGready, Elizabeth Ashley, Lucy Phaipun, Rina Patel, Kenneth Laing, Sornchai Looareesuwan, Nicholas J. White, François Nosten, Sanjeev Krishna
Other Authors: St George's University of London
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/21599
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/21599

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