Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites

by Shalini Nair, Denae Nash, Daniel Sudimack, Anchalee Jaidee, Marion Barends, Anne Catrin Uhlemann, Sanjeev Krishna, François Nosten, Tim J.C. Anderson
Published 2018

Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand

by Anne Catrin Uhlemann, Rose McGready, Elizabeth A. Ashley, Alan Brockman, Pratap Singhasivanon, Sanjeev Krishna, Nicholas J. White, François Nosten, Ric N. Price
Published 2018

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

by Ric N. Price, Anne Catrin Uhlemann, Alan Brockman, Rose McGready, Elizabeth Ashley, Lucy Phaipun, Rina Patel, Kenneth Laing, Sornchai Looareesuwan, Nicholas J. White, François Nosten, Sanjeev Krishna
Published 2018

Molecular and pharmacological determinants of the therapeutic response to artemether-lumefentrine in multidrug-resistant Plasmodium falciparum malaria

by Rie N. Price, Anne Catrin Uhlemann, Michela Van Vugt, Al Brockman, Robert Hutagalung, Shalini Nair, Denae Nash, Pratap Singhasivanon, Tim J.C. Anderson, Sanjeev Krishna, Nicholas J. White, François Noston
Published 2018

The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance

by James M. Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F. Gnädig, Charisse Flerida A. Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne Catrin Uhlemann, Ric N. Price, Grennady Wirjanata, Rintis Noviyanti, Patrick Tumwebaze, Roland A. Cooper, Philip J. Rosenthal, Laura M. Sanz, Francisco Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C. Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A. Fidock, Didier Leroy
Published 2022