Antimalarial activity of biflavonoids from Ochna integerrima

• Main Authors: Chikara Ichino, Hiroaki Kiyohara, Noppamas Soonthornchareonnon, Wongsatit Chuakul, Aki Ishiyama, Hitomi Sekiguchi, Miyuki Namatame, Kazuhiko Otoguro, Satoshi Omura, Haruki Yamada
• Other Authors: Kitasato University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/22892
• Institution: Mahidol University

During the screening of antimalarial substances, the 80% EtOH extract from the outer bark of Ochna integerrima Merr. (Ochnaceae) was shown to have a good anti-malarial activity (IC50 value: 6.5 μg/mL) whereas extracts from the inner barks of O. integerrima showed no antimalarial activity. Biflavanon...