Inhibition of malarial topoisomerase II in Plasmodium falciparum by antisense nanoparticles
New effective antimalarial agents are urgently needed due to increasing drug resistance of Plasmodium falciparum. Phosphorothioate antisense oligodeoxynucleotides (ODNs) silencing of malarial topoisomerase II gene have shown to possess promising features as anti malarial agents. In order to improve...
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Main Authors: | , , , , , , |
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Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/23900 |
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Institution: | Mahidol University |