Chloroquine resistant Plasmodium vivax: In vitro characterisation and association with molecular polymorphisms

• Main Authors: Rossarin Suwanarusk, Bruce Russell, Marina Chavchich, Ferryanto Chalfein, Enny Kenangalem, Varakorn Kosaisavee, Budi Prasetyorini, Kim A. Piera, Marion Barends, Alan Brockman, Usa Lek-Uthai, Nicholas M. Anstey, Emiliana Tjitra, François Nosten, Qin Cheng, Ric N. Price
• Other Authors: Charles Darwin University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23970
• Institution: Mahidol University

Background. Treatment failure of chloroquine for P. vivax infections has reached high levels in the eastern provinces of Indonesia, however, in vitro characterization of chloroquine resistance and its associated molecular profile have yet to be determined. Methods. Using a modified schizont maturati...