Protective effects of coenzyme Q10 on decreased oxidative stress resistance induced by simvastatin

The effects of simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl CoA reductase (HMG-CoA reductase), on oxidative stress resistance and the protective effects of coenzyme Q (CoQ) were investigated. When simvastatin was administered orally to mice, the levels of oxidized and reduced CoQ9 and CoQ...

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Bibliographic Details
Main Authors: Aikkarach Kettawan, Takayuki Takahashi, Ratchanee Kongkachuichai, Somsri Charoenkiatkul, Takeo Kishi, Tadashi Okamoto
Other Authors: Kobe Gakuin University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24012
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Institution: Mahidol University