Expression of β^E and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia

• Main Authors: Pranee Winichagoon, Saovaros Svasti, Pattanee Winichagoon, Chureeporn Chitchumroonchokchai, Suthat Fucharoen
• Other Authors: The Institute of Science and Technology for Research and Development, Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24892
• Institution: Mahidol University

This study described the expression of βE-globin in newborns heterozygous for HbE. Despite the lower level of HbE, the pattern of βE-globin gene expression was similar to βA- globin because the increase in HbE and HbA reached the peak level at the same time. A delayed decline of HbF was observed.