Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia

Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia

This study described the expression of βE-globin in newborns heterozygous for HbE. Despite the lower level of HbE, the pattern of βE-globin gene expression was similar to βA- globin because the increase in HbE and HbA reached the peak level at the same time. A delayed decline of HbF was observed.

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Main Authors: Pranee Winichagoon, Saovaros Svasti, Pattanee Winichagoon, Chureeporn Chitchumroonchokchai, Suthat Fucharoen
Other Authors: The Institute of Science and Technology for Research and Development, Mahidol University
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24892
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Institution: Mahidol University
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spelling th-mahidol.248922018-08-24T09:06:18Z Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia Pranee Winichagoon Saovaros Svasti Pattanee Winichagoon Chureeporn Chitchumroonchokchai Suthat Fucharoen The Institute of Science and Technology for Research and Development, Mahidol University Mahidol University Medicine This study described the expression of βE-globin in newborns heterozygous for HbE. Despite the lower level of HbE, the pattern of βE-globin gene expression was similar to βA- globin because the increase in HbE and HbA reached the peak level at the same time. A delayed decline of HbF was observed. 2018-08-24T02:06:18Z 2018-08-24T02:06:18Z 2007-05-01 Article Haematologica. Vol.92, No.5 (2007), 702-703 10.3324/haematol.10930 03906078 2-s2.0-34447302633 https://repository.li.mahidol.ac.th/handle/123456789/24892 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34447302633&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Pranee Winichagoon
Saovaros Svasti
Pattanee Winichagoon
Chureeporn Chitchumroonchokchai
Suthat Fucharoen
Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia
description This study described the expression of βE-globin in newborns heterozygous for HbE. Despite the lower level of HbE, the pattern of βE-globin gene expression was similar to βA- globin because the increase in HbE and HbA reached the peak level at the same time. A delayed decline of HbF was observed.
author2 The Institute of Science and Technology for Research and Development, Mahidol University
author_facet The Institute of Science and Technology for Research and Development, Mahidol University
Pranee Winichagoon
Saovaros Svasti
Pattanee Winichagoon
Chureeporn Chitchumroonchokchai
Suthat Fucharoen
format Article
author Pranee Winichagoon
Saovaros Svasti
Pattanee Winichagoon
Chureeporn Chitchumroonchokchai
Suthat Fucharoen
author_sort Pranee Winichagoon
title Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia
title_short Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia
title_full Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia
title_fullStr Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia
title_full_unstemmed Expression of β<sup>E</sup> and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia
title_sort expression of β<sup>e</sup> and γ-globin genes in infants heterozygous for hemoglobin e and double heterozygous for hemoglobin e and α-thalassemia
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/24892
_version_ 1763493988065607680

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