Single proline substitutions of selected helices of the Bacillus thuringiensis Cry4B toxin affect inclusion solubility and larvicidal activity

PCR-based mutagenesis was employed to investigate the role in toxicity of putative trans-membrane helices of the 130-kDa Cry4B mosquito-larvicidal delta-endotoxin produced by Bacillus thuringiensis subsp. israelensis. Mutant toxins with a single proline substitution in the central region of α5, α6 a...

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Bibliographic Details
Main Authors: I. Sramala, P. Uawithya, U. Chanama, S. Leetachewa, C. Krittanai, G. Katzenmeier, S. Panyim, C. Angsuthanasombat
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/25883
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Institution: Mahidol University