A new antimycobacterial, 3β-acetoxy-15α,22-dihydroxyhopane, from the insect pathogenic fungus Aschersonia tubulata

• Main Authors: S. Boonphong, P. Kittakoop, M. Isaka, P. Palittapongarnpim, A. Jaturapat, K. Danwisetkanjana, M. Tanticharoen, Y. Thebtaranonth
• Other Authors: Naresuan University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/26465
• Institution: Mahidol University

Bioassay-guided fractionation of the cell extract of the insect pathogenic fungus Aschersonia tubulata BCC 1785 led to the isolation of dustanin (1), 3β,15α,22-trihydroxyhopane (3), 5α,8α-epidioxy-24(R)-methylcholesta-6,22-diene-3β-ol (6), together with the new 3β-acetoxy-15α,22-dihydroxyhopane (4)....