The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis

The Aspergillus fumigatus δpmrA (Golgi apparatus Ca2+/Mn2+ P-type ATPase) strain has osmotically suppressible basal growth defects and cationic tolerance associated with increased expression of calcineurin pathway genes. Despite increased β-glucan and chitin content, it is hypersensitive to cell wal...

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Main Authors:	Nadthanan Pinchai, Praveen Rao Juvvadi, Jarrod R. Fortwendel, B. Zachary Perfect, Luise E. Rogg, Yohannes G. Asfaw, William J. Steinbach
Other Authors:	Duke University School of Medicine
Format:	Note
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Immunology and Microbiology
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/28774
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Institution:	Mahidol University

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spelling	th-mahidol.287742018-09-24T16:07:27Z The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis Nadthanan Pinchai Praveen Rao Juvvadi Jarrod R. Fortwendel B. Zachary Perfect Luise E. Rogg Yohannes G. Asfaw William J. Steinbach Duke University School of Medicine Mahidol University Biochemistry, Genetics and Molecular Biology Immunology and Microbiology The Aspergillus fumigatus δpmrA (Golgi apparatus Ca2+/Mn2+ P-type ATPase) strain has osmotically suppressible basal growth defects and cationic tolerance associated with increased expression of calcineurin pathway genes. Despite increased β-glucan and chitin content, it is hypersensitive to cell wall inhibitors but remains virulent, suggesting a role for PmrA in cation homeostasis and cell wall integrity. © 2010, American Society for Microbiology. All Rights Reserved. 2018-09-24T08:47:16Z 2018-09-24T08:47:16Z 2010-03-01 Note Eukaryotic Cell. Vol.9, No.3 (2010), 472-476 10.1128/EC.00378-09 15359778 2-s2.0-77649288776 https://repository.li.mahidol.ac.th/handle/123456789/28774 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77649288776&origin=inward
institution	Mahidol University
building	Mahidol University Library
continent	Asia
country	Thailand Thailand
content_provider	Mahidol University Library
collection	Mahidol University Institutional Repository
topic	Biochemistry, Genetics and Molecular Biology Immunology and Microbiology
spellingShingle	Biochemistry, Genetics and Molecular Biology Immunology and Microbiology Nadthanan Pinchai Praveen Rao Juvvadi Jarrod R. Fortwendel B. Zachary Perfect Luise E. Rogg Yohannes G. Asfaw William J. Steinbach The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis
description	The Aspergillus fumigatus δpmrA (Golgi apparatus Ca2+/Mn2+ P-type ATPase) strain has osmotically suppressible basal growth defects and cationic tolerance associated with increased expression of calcineurin pathway genes. Despite increased β-glucan and chitin content, it is hypersensitive to cell wall inhibitors but remains virulent, suggesting a role for PmrA in cation homeostasis and cell wall integrity. © 2010, American Society for Microbiology. All Rights Reserved.
author2	Duke University School of Medicine
author_facet	Duke University School of Medicine Nadthanan Pinchai Praveen Rao Juvvadi Jarrod R. Fortwendel B. Zachary Perfect Luise E. Rogg Yohannes G. Asfaw William J. Steinbach
format	Note
author	Nadthanan Pinchai Praveen Rao Juvvadi Jarrod R. Fortwendel B. Zachary Perfect Luise E. Rogg Yohannes G. Asfaw William J. Steinbach
author_sort	Nadthanan Pinchai
title	The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis
title_short	The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis
title_full	The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis
title_fullStr	The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis
title_full_unstemmed	The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis
title_sort	aspergillus fumigatus p-type golgi apparatus ca2+/mn2+ atpase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis
publishDate	2018
url	https://repository.li.mahidol.ac.th/handle/123456789/28774
_version_	1763495997544071168

The aspergillus fumigatus p-type golgi apparatus Ca2+/Mn2+ ATPase pmra is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis

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