High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia

• Main Authors: Tim J C Anderson, Shalini Nair, Standwell Nkhorna, Jeff T. Williams, Mallika Imwong, Poravuth Yi, Duong Socheat, Debashish Das, Kesinee Chotivanich, Nicholas P J Day, Nicholas J. White, Arjen M. Dondorp
• Other Authors: Texas Biomedical Research Institute
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/29691
• Institution: Mahidol University

In western Cambodia, malaria parasites clear slowly from the blood after treatment with artemisinin derivatives, but it is unclear whether this results from parasite, host, or other factors specific to this population. We measured heritability of clearance rate by evaluating patients infected with i...