Base excision DNA repair defect in thioredoxin-1 (Trx1)-deficient cells

Thioredoxin-1 (Trx1) is an antioxidant enzyme with a protective role in the removal of oxidative stress. We investigated the mechanism by which the redox modulator Trx1 affects base excision repair (BER) activity to understand the protective role of Trx1. We constructed a Trx1 knockdown system to de...

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Bibliographic Details
Main Authors: Hye Lim Kim, Preeyaporn Koedrith, Sang Min Lee, Yeo Jin Kim, Young Rok Seo
Other Authors: Dongguk University, Seoul
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31176
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Institution: Mahidol University

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