Dengue virus neutralization and antibody-dependent enhancement activities of human monoclonal antibodies derived from dengue patients at acute phase of secondary infection

• Main Authors: Tadahiro Sasaki, Chayanee Setthapramote, Takeshi Kurosu, Mitsuhiro Nishimura, Azusa Asai, Magot D. Omokoko, Chonlatip Pipattanaboon, Pannamthip Pitaksajjakul, Kriengsak Limkittikul, Arunee Subchareon, Panjaporn Chaichana, Tamaki Okabayashi, Itaru Hirai, Pornsawan Leaungwutiwong, Ryo Misaki, Kazuhito Fujiyama, Ken ichiro Ono, Yoshinobu Okuno, Pongrama Ramasoota, Kazuyoshi Ikuta
• Other Authors: Osaka University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/31914
• Institution: Mahidol University

Public health concern about dengue diseases, caused by mosquito-borne infections with four serotypes of dengue virus (DENV-1-DENV-4), is escalating in tropical and subtropical countries. Most of the severe dengue cases occur in patients experiencing a secondary infection with a serotype that is diff...