Human monoclonal ScFv that bind to different functional domains of M2 and inhibit H5N1 influenza virus replication

Background: Novel effective anti-influenza agent that tolerates influenza virus antigenic variation is needed. Highly conserved influenza virus M2 protein has multiple pivotal functions including ion channel activity for vRNP uncoating, anti-autophagy and virus assembly, morphogenesis and release. T...

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Main Authors: Tippawan Pissawong, Santi Maneewatch, Kanyarat Thueng-In, Potjanee Srimanote, Fonthip Dong-Din-On, Jeeraphong Thanongsaksrikul, Thaweesak Songserm, Pongsri Tongtawe, Kunan Bangphoomi, Wanpen Chaicumpa
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31920
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Institution: Mahidol University