Effect of simvastatin on monocyte chemoattractant protein-1 expression in endometriosis patients: a randomized controlled trial

• Main Authors: Wanwisa Waiyaput, Somphoch Pumipichet, Sawaek Weerakiet, Sasivimol Rattanasiri, Areepan Sophonsritsuk
• Other Authors: Mahidol University. Department of Obstetrics & Gynecology, Ramathibodi Hospital . Reproductive Endocrinology and Infertility Unit
• Format: Article
• Language: English
• Published: 2017
• Subjects: Endometriosis; Simvastatin; Laparoscopy; Serum MCP-1; MCP-1 gene expression; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/3229
• Institution: Mahidol University

Background: Simvastatin is a promising new drug for the treatment of endometriosis. It is a cholesterol-lowering drug that acts by inhibiting HMG-CoA reductase, resulting in a decrease in mevalonate, a precursor of cholesterol and monocyte chemoattractant protein-1 (MCP-1). This study investigated...