A flow cytometric analysis of the inhibition of platelet reactivity due to nitrite reduction by deoxygenated erythrocytes

• Main Authors: Krittapoom Akrawinthawong, Ji Won Park, Barbora Piknova, Nathawut Sibmooh, Suthat Fucharoen, Alan N. Schechter
• Other Authors: National Institute of Diabetes and Digestive and Kidney Diseases
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/33036
• Institution: Mahidol University

Nitric oxide (NO), a small gas molecule, has long been known to be a potent inhibitor of platelet function but the physiological and pathological implications of platelet inhibition by NO have not been well clarified. We recently showed that the addition of nitrite to platelet-rich plasma in the pre...