Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: A randomised, controlled, double-blind, dose-ranging trial

Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: A randomised, controlled, double-blind, dose-ranging trial

Background: Primaquine is the only available drug that clears mature Plasmodium falciparum gametocytes in infected human hosts, thereby preventing transmission of malaria to mosquitoes. However, concerns about dose-dependent haemolysis in people with glucose-6-phosphate dehydrogenase (G6PD) deficien...

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Bibliographic Details
Main Authors: Alice C. Eziefula, Teun Bousema, Shunmay Yeung, Moses Kamya, Asiphas Owaraganise, Grace Gabagaya, John Bradley, Lynn Grignard, Kjerstin H.W. Lanke, Humphrey Wanzira, Arthur Mpimbaza, Samuel Nsobya, Nicholas J. White, Emily L. Webb, Sarah G. Staedke, Chris Drakeley
Other Authors: London School of Hygiene & Tropical Medicine
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/34306
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/34306

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