Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: A randomised, controlled, double-blind, dose-ranging trial
Background: Primaquine is the only available drug that clears mature Plasmodium falciparum gametocytes in infected human hosts, thereby preventing transmission of malaria to mosquitoes. However, concerns about dose-dependent haemolysis in people with glucose-6-phosphate dehydrogenase (G6PD) deficien...
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Main Authors: | Alice C. Eziefula, Teun Bousema, Shunmay Yeung, Moses Kamya, Asiphas Owaraganise, Grace Gabagaya, John Bradley, Lynn Grignard, Kjerstin H.W. Lanke, Humphrey Wanzira, Arthur Mpimbaza, Samuel Nsobya, Nicholas J. White, Emily L. Webb, Sarah G. Staedke, Chris Drakeley |
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Other Authors: | London School of Hygiene & Tropical Medicine |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/34306 |
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Institution: | Mahidol University |
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