Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): A multicentre, double-blind, randomised, phase 2b dose-selection study

Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): A multicentre, double-blind, randomised, phase 2b dose-selection study

Background Clinical eff ectiveness of previous regimens to treat Plasmodium vivax infection have been hampered by compliance. We aimed to assess the dose-response, safety, and tolerability of single-dose tafenoquine plus 3-day chloroquine for P vivax malaria radical cure. Methods In this double-blin...

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Main Authors: Alejandro Llanos-Cuentas, Marcus V. Lacerda, Ronnatrai Rueangweerayut, Srivicha Krudsood, Sandeep K. Gupta, Sanjay K. Kochar, Preetam Arthur, Nuttagarn Chuenchom, Jörg J. Möhrle, Stephan Duparc, Cletus Ugwuegbulam, Jörg Peter Kleim, Nick Carter, Justin A. Green, Lynda Kellam
Other Authors: Universidad Peruana Cayetano Heredia
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/34830
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/34830

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