Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway

• Main Authors: Weijian Ye, Marvin Chew, Jue Hou, Fritz Lai, Stije J. Leopold, Hooi Linn Loo, Aniruddha Ghose, Ashok K. Dutta, Qingfeng Chen, Eng Eong Ooi, Nicholas J. White, Arjen M. Dondorp, Peter Preiser, Jianzhu Chen
• Other Authors: Singapore-MIT Alliance
• Format: Article
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/45047
• Institution: Mahidol University

© 2018 Ye et al. http://creativecommons.org/licenses/by/4.0/. Natural killer (NK) cells provide the first line of defense against malaria parasite infection. However, the molecular mechanisms through which NK cells are activated by parasites are largely unknown, so is the molecular basis underlying...