Cysteinyl leukotriene receptor antagonists induce apoptosis and inhibit proliferation of human glioblastoma cells by downregulating b-cell lymphoma 2 and inducing cell cycle arrest

• Main Authors: Pannaree Piromkraipak, Tipparat Parakaw, Suttinee Phuagkhaopong, Sirada Srihirun, Sukumal Chongthammakun, Kulathida Chaithirayanon, Pornpun Vivithanaporn
• Other Authors: Mahidol University
• Format: Article
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/45277

© 2018, Canadian Science Publishing. All rights reserved. Glioblastoma is the most aggressive type of brain cancer with the highest proliferation, invasion, and migration. Montelukast and zafirlukast, 2 widely used leukotriene receptor antagonists (LTRAs) for asthma treatment, inhibited invasion and...