Genomic structure and diversity of Plasmodium falciparum in Southeast Asia reveal recent parasite migration patterns

• Main Authors: Amol C. Shetty, Christopher G. Jacob, Fang Huang, Yao Li, Sonia Agrawal, David L. Saunders, Chanthap Lon, Mark M. Fukuda, Pascal Ringwald, Elizabeth A. Ashley, Kay Thwe Han, Tin Maung Hlaing, Myaing M. Nyunt, Joana C. Silva, Kathleen E. Stewart, Christopher V. Plowe, Timothy D. O’Connor, Shannon Takala-Harrison, Harald Noedl, Wasif A. Khan, Paul Newton, Myat P. Kyaw, Nicholas J. White, Arjen M. Dondorp, Nicholas P. Day, Charles J. Woodrow, Mehul Dhorda, M. Abul Faiz, Rick M. Fairhurst, Pharath Lim, Rupam Tripura, Mayfong Mayxay, Ye Htut, Francois Nosten, Aung Pyae Phyo, Sasithon Pukrittayakamee, Tran Tinh Hien, Nguyen Thanh Thuy Nhien, Olugbenga A. Mokuolu, Caterina I. Fanello, Marie A. Onyamboko
• Other Authors: Medizinische Universitat Wien, Zentrum für Pathophysiologie, Infektiologie und Immunologie
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/50027
• Institution: Mahidol University

© 2019, The Author(s). Estimates of Plasmodium falciparum migration may inform strategies for malaria elimination. Here we elucidate fine-scale parasite population structure and infer recent migration across Southeast Asia using identity-by-descent (IBD) approaches based on genome-wide single nucleo...