Inhibition of Tumor Growth against Chemoresistant Cholangiocarcinoma by a Proapoptotic Peptide Targeting Interleukin-4 Receptor

Inhibition of Tumor Growth against Chemoresistant Cholangiocarcinoma by a Proapoptotic Peptide Targeting Interleukin-4 Receptor

Cholangiocarcinoma (CCA) has a poor prognosis and high chemoresistance. Interleukin-4 receptor (IL-4R) is overexpressed in several cancer cells and plays a crucial role in tumor progression and drug resistance. IL4RPep-1, an IL-4R-binding peptide, has been identified by phage display and used for tu...

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Bibliographic Details
Main Authors: Uttapol Permpoon, Fatima Khan, Sri Murugan Poonkavithai Vadevoo, Smriti Gurung, Gowri Rangaswamy Gunassekaran, Min Jong Kim, Sang Hyun Kim, Peti Thuwajit, Byungheon Lee
Other Authors: Faculty of Medicine, Siriraj Hospital, Mahidol University
Format: Article
Published: 2020
Subjects:
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/59855
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/59855

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