Production of human embryonic kidney 293T cells stably expressing C-X-C chemokine receptor type 4 (CXCR4) as a screening tool for anticancer lead compound targeting CXCR4

Aim: The C-X-C chemokine-receptor type 4 (CXCR4) is an emerging target for cancer drug discovery due to its high expression in cancer cells. The present study aimed to produce CXCR4 overexpressing HEK293T cells for a non-radioactive binding assay as a platform to identify drug candidates targeting C...

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Bibliographic Details
Main Authors: Dinh Thi Thai Ha, Kittirat Glab-ampai, Pornchai Rojsitthisak, Opa Vajragupta
Other Authors: Siriraj Hospital
Format: Article
Published: 2022
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/73232
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Institution: Mahidol University