Production of human embryonic kidney 293T cells stably expressing C-X-C chemokine receptor type 4 (CXCR4) as a screening tool for anticancer lead compound targeting CXCR4
Aim: The C-X-C chemokine-receptor type 4 (CXCR4) is an emerging target for cancer drug discovery due to its high expression in cancer cells. The present study aimed to produce CXCR4 overexpressing HEK293T cells for a non-radioactive binding assay as a platform to identify drug candidates targeting C...
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Main Authors: | Dinh Thi Thai Ha, Kittirat Glab-ampai, Pornchai Rojsitthisak, Opa Vajragupta |
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Other Authors: | Siriraj Hospital |
Format: | Article |
Published: |
2022
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/73232 |
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Institution: | Mahidol University |
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