Development of a Novel Anti-CD19 CAR Containing a Fully Human scFv and Three Costimulatory Domains

Development of a Novel Anti-CD19 CAR Containing a Fully Human scFv and Three Costimulatory Domains

Second-generation anti-CD19-chimeric antigen receptor T cells (anti-CD19-CAR2 T cells) are effective for treating B-cell malignancies; however, anti-CD19-CAR2 T cells can induce human anti-mouse immune responses because anti-CD19 single-chain variable fragment (scFv) in the CAR molecules is derived...

Full description

Saved in:
Bibliographic Details
Main Authors: Yupanun Wutti-in, Jatuporn Sujjitjoon, Nunghathai Sawasdee, Aussara Panya, Katesara Kongkla, Pornpimon Yuti, Petlada Yongpitakwattana, Chutamas Thepmalee, Mutita Junking, Thaweesak Chieochansin, Naravat Poungvarin, Montarop Yamabhai, Pa Thai Yenchitsomanus
Other Authors: Siriraj Hospital
Format: Article
Published: 2022
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/73465
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University

Internet

https://repository.li.mahidol.ac.th/handle/123456789/73465

Similar Items