A Quantitative Approach to Unravel the Role of Host Genetics in IgG-FcγR Complex Formation After Vaccination
Fc-mediated immune functions have been correlated with protection in the RV144 HIV vaccine trial and are important for immunity to a range of pathogens. IgG antibodies (Abs) that form complexes with Fc receptors (FcRs) on innate immune cells can activate Fc-mediated immune functions. Genetic variati...
Saved in:
Main Authors: | Melissa M. Lemke, Robert M. Theisen, Emily R. Bozich, Milla R. McLean, Christina Y. Lee, Ester Lopez, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Sven Kratochvil, Bruce D. Wines, P. Mark Hogarth, Stephen J. Kent, Amy W. Chung, Kelly B. Arnold |
---|---|
Other Authors: | Faculty of Tropical Medicine, Mahidol University |
Format: | Article |
Published: |
2022
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/74156 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
Similar Items
-
A systems approach to elucidate personalized mechanistic complexities of antibody-Fc receptor activation post-vaccination
by: Melissa M. Lemke, et al.
Published: (2022) -
A Quantitative Approach to Unravel the Role of Host Genetics in IgG-FcγR Complex Formation After Vaccination
by: Lemke M.M.
Published: (2023) -
Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines
by: Amy W. Chung, et al.
Published: (2018) -
IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees
by: Stephanie Fischinger, et al.
Published: (2020) -
Protein-based, but not viral vector alone, HIV vaccine boosting drives an IgG1-biased polyfunctional humoral immune response
by: Stephanie Fischinger, et al.
Published: (2020)