The circulatory small non-coding RNA landscape in community-acquired pneumonia on intensive care unit admission

• Main Authors: Hina N. Khan, Aldo Jongejan, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Olaf L. Cremer, Marc J. Bonten, Tom van der Poll, Brendon P. Scicluna
• Other Authors: University Medical Center Utrecht
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76093
• Institution: Mahidol University

Community-acquired pneumonia (CAP) is a major cause of sepsis. Despite several clinical trials targeting components of the inflammatory response, no specific treatment other than antimicrobial therapy has been approved. This argued for a deeper understanding of sepsis immunopathology, in particular...